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首页> 外文期刊>亚太热带医药杂志（英文版） >Assessment of compliance to sulfadoxine-pyrimethamine 18 months after phasing out chloroquine in Mkuranga District, Coast region-Tanzania
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Assessment of compliance to sulfadoxine-pyrimethamine 18 months after phasing out chloroquine in Mkuranga District, Coast region-Tanzania

机译：坦桑尼亚沿海地区姆库兰加区淘汰氯喹后18个月对磺胺多辛-乙胺嘧啶的依从性评估

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Objective:To observe and assess the compliance to sulfadoxine-pyrimethamine (SP) one and a half years after phasing out chloroquine (CQ) in Mkuranga District, Coast region, Tanzania. Methods:A randomly controlled baseline community study was conducted in rural areas of Mkuranga district, Tanzania. Semi-structured questionnaire consisted of open-and closed-ended questions including home stocking, home use, last fever episodes and treatment of underfives with malaria using CQ or SP. Results:The prevalence of fever or reported fever rate during the last 48 hours by their mothers or guardians was high (70%). Of all 117 blood samples, only 8 children after drug analysis were found to have CQ and 13 had SP concentrations within their blood respectively. None of these blood drug levels were above therapeutic ranges. Conclusions:Community interventions are urgently needed in rural communities and should specifically target households nucleus on early malaria fever recognition and provision of recommended antimalarials for the sick underfive children. However, sadly, there was an increase in underweight and undernourishment in the study areas, probably because of malaria in the area and poverty which are associated with poor nutrition in these youngsters.
机译：目的：观察并评估坦桑尼亚沿海地区姆库兰加区淘汰氯喹（CQ）一年半后对磺胺多辛-乙胺嘧啶（SP）的依从性。方法：在坦桑尼亚姆库兰加区的农村地区进行了一项随机对照的基线社区研究。半结构化问卷由开放式和封闭式问题组成，包括家庭饲养，家庭使用，上次发烧发作以及使用CQ或SP治疗疟疾未成年人。结果：母亲或监护人在过去48小时内发烧或报告的发烧率很高（70％）。在所有117份血液样本中，经过药物分析后仅发现8名儿童的血液中分别含有CQ和13名儿童的SP浓度。这些血液药物水平均未超过治疗范围。结论：农村社区迫切需要社区干预，这些干预应专门针对家庭核心，以早期识别疟疾热，并为患病的5岁以下儿童提供推荐的抗疟疾药物。但是，令人遗憾的是，研究区的体重过轻和营养不良的情况有所增加，这可能是因为该地区的疟疾和贫困与这些年轻人的营养不良有关。

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  • 来源
    《亚太热带医药杂志（英文版）》 |2010年第006期|451-453|共3页
  • 作者

    Stephen ED Nsimba; Phare G Mujinja;

  • 作者单位

    Prospective College of Health&Allied Sciences CHAS, School 0f Medicine, P. 0. Box 395, Dodoma, Tanzania-East Africa;

    Muhimbili University of Health and Allied Sciences, School of Public Health&Social Sciences, P. 0. Box 65015, Dar-es-Salaam Tanzania;

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