Multidrug resistant Psudomonas aeruginosa infections complicating surgical wounds and the potential challenges in managing post-operative wound infections:University of Calabar Teaching Hospital experience

Jombo GT; Akpan S; Epoke J; Denen Akaa P; Odey F

首页> 外文期刊>亚太热带医药杂志（英文版） >Multidrug resistant Psudomonas aeruginosa infections complicating surgical wounds and the potential challenges in managing post-operative wound infections:University of Calabar Teaching Hospital experience

【24h】

Multidrug resistant Psudomonas aeruginosa infections complicating surgical wounds and the potential challenges in managing post-operative wound infections:University of Calabar Teaching Hospital experience

机译：铜绿假单胞菌的多药耐药性感染使手术伤口复杂化，并且在处理术后伤口感染方面存在潜在挑战：卡拉巴尔大学教学医院的经验

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

Objective:To ascertain the antimicrobial susceptibility profile of Pseudomonas aeruginosa (P. aeruginosa) recovered from surgical site infections (SSIs). Methods:The study was retrospective in nature and was compiled for a period of five years (1st February, 2004-31st January, 2009). Data were generated from the culture of post-operative wound swab specimens by the microbiology laboratory of University of Calabar Teaching Hospital. Relevant information from the patients’ records was compiled, such as age, gender, type of surgical procedure, microorganisms recovered and their antibiotic sensitivity patterns. Obtained data was analysed by using Epi Info 6 statistical software. Results:Of the 4 533 wound swab specimens processed, 673 were culture positive and P. aeruginosa was recovered from 13.1%of the culture positive specimens with its rate of recovery decreasing with age progression (P<0.05) but with no gender difference (P>0.05). Most of the P. aeruginosa isolates were from general surgery wards and least from orthopaedic wards. Ofloxacin, ceftriaxone and augmentin were the most active antibiotics while ampicillin, tetracycline and co-trimoxazole were the least active antibiotics, with no antibiotic having a 100%activity against the organism. Conclusions:In view of the high resistance displayed by P. aeruginosa recovered from SSIs, adequate antiseptic procedures should be entrenched to avoid colonization of surgical wounds by this microorganism as well as others with similar sensitivity profile. Ofloxacin, ceftriaxone and augmentin may be considered for prevention of P.aeruginosa infection.

机译：目的：确定从手术部位感染（SSI）中恢复的铜绿假单胞菌（P. aeruginosa）的抗菌药敏性。方法：本研究为回顾性研究，为期五年（2004年2月1日至2009年1月31日）。数据是由卡拉巴尔大学教学医院的微生物实验室根据术后伤口拭子标本的培养产生的。收集了患者记录中的相关信息，例如年龄，性别，手术程序类型，回收的微生物及其抗生素敏感性模式。使用Epi Info 6统计软件分析获得的数据。结果：在处理过的4 533个伤口拭子标本中，有673例培养阳性，从13.1％的培养阳性标本中检出铜绿假单胞菌，其恢复率随年龄的增长而降低（P <0.05），但无性别差异（P > 0.05）。铜绿假单胞菌的大多数分离株来自普通外科病房，最少来自骨科病房。氧氟沙星，头孢曲松和增强素是活性最高的抗生素，氨苄西林，四环素和复方新诺明是活性最低的抗生素，没有一种抗生素对生物体的活性为100％。结论：鉴于从SSI中回收的铜绿假单胞菌显示出很高的抗药性，应采取适当的防腐措施，以避免这种微生物以及其他敏感性相似的细菌在外科伤口上定植。可以考虑使用氧氟沙星，头孢曲松和增强素来预防铜绿假单胞菌感染。

著录项

来源
《亚太热带医药杂志（英文版）》 |2010年第006期|479-482|共4页
作者
Jombo GT; Akpan S; Epoke J; Denen Akaa P; Odey F;
展开▼
作者单位

Department of Medical Microbiology and Parasitology, College of Health Sciences, Benue State University, PMB 102119 Makurdi, Nigeria;

Department of Medical Microbiology and Parasitology, College of Medical Sciences, University of Calabar, PMB 1115 Calabar, Nigeria;

Department of Medical Microbiology and Parasitology, College of Medical Sciences, University of Calabar, PMB 1115 Calabar, Nigeria;

Department of Surgery, College of Health Sciences, Benue state University, Makurdi, PMB 102119 Makurdi, Nigeria;

Department of Paediatrics, College of Medical Sciences, University of Calabar, PMB 1115 Calabar, Nigeria;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词

Multidrug resistant Psudomonas aeruginosa infections complicating surgical wounds and the potential challenges in managing post-operative wound infections:University of Calabar Teaching Hospital experience

摘要

著录项

相关主题

期刊订阅