Anthelmintic activity of Saba senegalensis(A.DC.) Pichon (Apocynaceae) extract against adult worms and eggs of Haemonchus contortus

Mohamed; Bonewendé; Belemlilga; Aristide; Traoré; Sylvin; Ouédraogo; Adama; Kaboré; Hamidou; Hamadou; Tamboura; Innocent; Pierre; Guissou

首页> 中文期刊> 《亚太热带生物医学杂志：英文版》 >Anthelmintic activity of Saba senegalensis(A.DC.) Pichon (Apocynaceae) extract against adult worms and eggs of Haemonchus contortus

Anthelmintic activity of Saba senegalensis(A.DC.) Pichon (Apocynaceae) extract against adult worms and eggs of Haemonchus contortus

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Objective: To evaluate the anthelmintic property of Saba senegalensis（A.DC） Pichon（Apocynaceae）（S. senegalensis） on Haemonchus contortus that is traditionally used in Burkina Faso for its gastrointestinal parasites treatment.Methods: The lyophilized aqueous decoction of leaves of S. senegalensis at concentrations of 0.10, 1.00, 3.00, 10.00 and 15.00 mg/m L was used on eggs and adult worms of Haemonchus contortus collected from gastrointestinal tract of small ruminant.Results: The LC50 on adult worms was 6.79 mg/m L and 3.25 mg/m L for the leaves of S. senegalensis and the levamisole（reference drug）, respectively. Inhibition of hatching assay showed a concentration-dependent manner with an inhibition of 93.63% at the concentration of 15.00 mg/m L of S. senegalensis.Conclusions: These results indicate that the aqueous extract of S. senegalensis possesses an anthelmintic property and may justify its use in traditional medicine for the treatment of gastrointestinal parasites.

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《亚太热带生物医学杂志：英文版》 |2016年第011期|P.945-949|共5页
作者
Mohamed; Bonewendé; Belemlilga; Aristide; Traoré; Sylvin; Ouédraogo; Adama; Kaboré; Hamidou; Hamadou; Tamboura; Innocent; Pierre; Guissou;
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Laboratoire de Développement du Médicament, Centre de recherche sur le médicament, Ecole Doctorale de la Santé,Université de Ouagadougou, Ecole Doctorale de Santé;

Département Médecine Pharmacopée Traditionnelles–Pharmacie (MEPHATRA-Ph), Institut de Recherche en Sciences de la Santé (IRSS/CNRST);

Département Productions Animales, Institut de l’Environnement et de Recherches Agricoles(INERA/CNRST);

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Anthelmintic activity of Saba senegalensis(A.DC.) Pichon (Apocynaceae) extract against adult worms and eggs of Haemonchus contortus

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