Reduced graphene oxide-grafted bovine serum albumin/bredigite nanocomposites with high mechanical properties and excellent osteogenic bioactivity for bone tissue engineering

Esfandyar Askari; Mohammad Rasouli; Seyedeh F.Darghiasi; Seyed M.Naghib; Yasser Zare; Kyong Y.Rhee

首页> 中文期刊> 《生物设计与制作(英文)》 >Reduced graphene oxide-grafted bovine serum albumin/bredigite nanocomposites with high mechanical properties and excellent osteogenic bioactivity for bone tissue engineering

Reduced graphene oxide-grafted bovine serum albumin/bredigite nanocomposites with high mechanical properties and excellent osteogenic bioactivity for bone tissue engineering

开具论文收录证明 >>

期刊封面封底目录下载 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

The optimization of the scaffolds to provide a suitable matrix and accelerate the regeneration process is vital for bone tissue engineering.However,poor mechanical and biological characteristics remain the primary challenges that must be addressed.For example,although bredigite(Br)has shown great potential for application in bone tissue engineering,it easily fails in replacement.In the present work,these challenges are addressed by reinforcing the Br matrix with nanosheets of graphene oxide(rGO)that have been reduced by bovine serum albumin(BSA)in order to enhance the mechanical properties and biological behavior.The reduction of graphene oxide by BSA improves the water stability of the nanosheets and provides an electrostatic interaction between theBSA-rGO nanosheets and theBr particles.The high thermal conductivity of theBSA-rGO nanosheets decreases the porosity of the Br by transferring heat to the core of the tablet.Furthermore,the addition of BSA-rGO nanosheets into the Br matrix enhances the adhesion of G-292 cells on the surface of the tablets.These findings suggest that the tablet consisting of BSA-rGO-reinforced Br has encouraging potential for application in bone tissue engineering.

著录项

来源
《生物设计与制作(英文)》 |2021年第2期|P.243-257|共15页
作者
Esfandyar Askari; Mohammad Rasouli; Seyedeh F.Darghiasi; Seyed M.Naghib; Yasser Zare; Kyong Y.Rhee;
展开▼
作者单位

Nanotechnology Department School of Advanced Technologies Iran University of Science and Technology(IUST) P.O.Box 16846-13114 Tehran IranBiomaterials and Tissue Engineering Research Group Department of Interdisciplinary Technologies Breast Cancer Research Center Motamed Cancer Institute ACECR Tehran Iran;

Nanotechnology Department School of Advanced Technologies Iran University of Science and Technology(IUST) P.O.Box 16846-13114 Tehran Iran;

Nanotechnology Department School of Advanced Technologies Iran University of Science and Technology(IUST) P.O.Box 16846-13114 Tehran Iran;

Nanotechnology Department School of Advanced Technologies Iran University of Science and Technology(IUST) P.O.Box 16846-13114 Tehran Iran;

Biomaterials and Tissue Engineering Research Group Department of Interdisciplinary Technologies Breast Cancer Research Center Motamed Cancer Institute ACECR Tehran Iran;

Department of Mechanical Engineering College of Engineering Kyung Hee University Yongin 446-701 Republic of Korea;

展开▼
原文格式 PDF
正文语种 chi
中图分类工程材料学;
关键词
Bovine serum albumin(BSA); Reduced graphene oxide(rGO); Bredigite; Mechanical properties; Bone tissue engineering;

机译：牛血清白蛋白（BSA）;氧化石墨烯（RGO）;BREDIGITE;机械性能;骨组织工程;

Reduced graphene oxide-grafted bovine serum albumin/bredigite nanocomposites with high mechanical properties and excellent osteogenic bioactivity for bone tissue engineering

摘要

著录项

相关主题

期刊订阅