首页> 中文期刊> 《生物医学与环境科学:英文版》 >Protective Effect of Schisanhenol Against Oxygen Radical Induced Mitochondrial Toxicity on Rat Heart and Liver

Protective Effect of Schisanhenol Against Oxygen Radical Induced Mitochondrial Toxicity on Rat Heart and Liver

         

摘要

Schisanhenol(SAL)had been shown to have poent antioxidant activities.The protective effects of SAL against oxygen radical induced mitochondrial injuries of rat heart and liver were investigated in the present study.The ferrous-cysteine induced mitochondrial lipid peroxidation was significantly inhibited by SAL.while the loss of ATP ase activity inducd by the lipid peroxidation was prevented.The rididification of mitochondrial membrane,aw well as swelling,lysis and disintegration of the mitochondria induced by ferrous-cysteine were all significantly inhibited by SAL.These results further confirm that SAL possesses antioxidant activity.

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