Decrease in Serum Amyloid a Protein Levels Following Three-month Stays in Negatively Charged Particle-dominant Indoor Air Conditions

Suni Lee; Shoko Yamamoto; Yasumitsu Nishimura; Hidenori Matsuzaki; Kei Yoshitome; Tamayo Hatayama; Miho Ikeda; YU Min; Nagisa Sada; Naoko Kumagai-Takei; Takemi Otsuki

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Decrease in Serum Amyloid a Protein Levels Following Three-month Stays in Negatively Charged Particle-dominant Indoor Air Conditions

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Objective The changes in serum adipokines and cytokines related to oxidative stress were examined during 3 months ‘Off to On' and ‘On to Off' periods using negatively charged particle-dominant indoor air conditions(NCPDIAC).Methods Seven volunteers participated in the study,which included ‘OFF to 3 months ON' periods(ON trials) for a total of 16 times,and ‘ON to 3 months OFF'(OFF trials) periods for a total of 13 times.Results With the exception of one case,serum amyloid A(SAA) levels decreased significantly during the ON trials.Conclusion Considering that SAA is an acute phase reactive protein such as C reactive protein(CRP),this observed decrease might indicate the prevention of cardiovascular and atherosclerotic changes,since an increase in high-sensitive CRP is associated with the subsequent detection of these events.

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《生物医学与环境科学：英文版》 |2018年第5期|335-342|共8页
作者
Suni Lee; Shoko Yamamoto; Yasumitsu Nishimura; Hidenori Matsuzaki; Kei Yoshitome; Tamayo Hatayama; Miho Ikeda; YU Min; Nagisa Sada; Naoko Kumagai-Takei; Takemi Otsuki;
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作者单位

Department of Hygiene;

Kawasaki Medical School;

577 Mastushima;

Kurashiki 701-0192;

Japan;

Department of Occupational and Environmental Health Science;

School of Public Health;

School of Public Health;

Peking University Health Science Center;

Bejing 100191;

China;

Department of Occupational Diseases;

Zhejiang Academy of Medical Sciences;

Hangzhou 310013;

Zhejiang;

China;

Department of Biophysical Chemistry;

Graduate School of Medicine;

Dentistry and Pharmaceutical Sciences;

Okayama University;

1-1-1 Tsushimanaka;

Kita-Ku;

Okayama 700-8530;

Japan;

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原文格式 PDF
正文语种 chi
中图分类蔬菜园艺;
关键词
空气条件; 浆液; 室内; 粒子; 否定; 淀粉; 蛋白质; cytokines;

Decrease in Serum Amyloid a Protein Levels Following Three-month Stays in Negatively Charged Particle-dominant Indoor Air Conditions

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