首页> 中文期刊> 《生物医学与环境科学:英文版》 >Mutation of the KIT Gene, excluding Exon 11, in Gastrointestinal Stromal Tumors

Mutation of the KIT Gene, excluding Exon 11, in Gastrointestinal Stromal Tumors

         

摘要

Gastrointestinal stromal tumors(GISTs)are derived from the interstitial cells of Cajal,and are the most common mesenchymal tumors of the gastrointestinal tract[1].KIT proto-oncogene,receptor tyrosine kinase(KIT),and platelet-derived growth factor receptor alpha(PDGFRA)gene mutations are found in approximately 85%–90% cases of GIST.

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