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Rapid Detection of Yersinia pestis by Real-time Recombinase-aided Amplification

         

摘要

Yersinia pestis,the causative agent of bubonic and pneumonic plague,is considered to be one of the most dangerous and deadly pathogenic bacteria in the world[1].Y.pestis is classified as a category A pathogen by the United States Center for Disease Control and Prevention because of its ease of aerosol-to-human transmission,high lethality,and potential for mass casualties as a biological warfare agent[2].Therefore,both prevention and treatment require the development of a rapid,sensitive,and specific method to detect Y.pestis.

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