信号放大技术因其能实现低浓度分子检测，灵敏度高而在多个研究领域发展非常迅速。而适体作为识别分子已成功应用于多种生物传感器平台，在医疗诊断、环境检测、生化分析中显示出良好的应用前景。近年来，以适体为识别元件的生物传感器越来越受到人们的关注。综述了近3年来基于信号放大技术的适体生物传感器研究新发展。%Signal amplification technology has grown immensely in many fields because of its high accuracy and sensitivity at low concentrations. As a recognized molecule, aptamer has been used on many biosensors, and also has shown a good prospect in medical diagnosis, environmental monitoring and biological analysis. In recent years, biosensors with aptamer as recognized molecule has attracted more and more attention. The new research development of aptamer biosensors based on signal amplification technology in nearly three years was summarized especially.
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