首页> 中文期刊> 《肝癌研究(英文版)》 >The role of APOBEC3B in the development of hepatocellular carcinoma should be investigated with the consideration of hepatitis B virus evolution

The role of APOBEC3B in the development of hepatocellular carcinoma should be investigated with the consideration of hepatitis B virus evolution

         

摘要

The chronic infection of hepatitis B virus (HBV) is the major cause of hepatocellular carcinoma (HCC) globally[1]. In Eastern China, chronic HBV infection contributes to 87.5% of HCC whereas chronic hepatitis C virus (HCV) infection contributes to 1.7%[2]. The mortality of HCC has increased in Europe and America over recent decades[3]. Although the infection of HCV is the leading cause of HCC in most European and American countries, the contribution of HBV is increasing possibly due to immigration[3].

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