@@ 咪唑和三氮唑衍生物大多具有重要的生物活性,如抗惊厥,细菌抑制活性,抗真菌活性[1-3],其中一些衍生物是性能优良的医药或农药.作为医药唑类抗真菌药有较广的抗真菌谱,可用于局部使用,治疗皮肤真菌感染和酵母菌感染,部分药物可口服治疗全身真菌感染[4].%Novel triazole and imidazole derivatives containing biphenyl were synthesized via F-C acylation, substitute reaction, reduction reaction starting from 2, 4-difluorinbiphenyl. Title compounds 3,4, 5 and 6 possess potential biological activity. The structures of novel compounds were confirmed by 1H NMR、IR 、MS spectra and elemental analyses.
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