Objective To analyze the efficacy and safety of mezlocillin combine with probiotics in treatment of pediatric infectious diarrhea. Methods 92 cases of children with infectious diarrhea in our hospital divided into two group, control group received mezlocillin monotherapy, the observation group received mezlocillin combined with probiotics treatment, stool frequency, stool normal time and total clinical efficiency were compared. Results The total effective rate in observer group was 95.7%, signiifcantly higher than control group 82.6%(P<0.05). Observer group stool stool frequency and recovery time was signiifcantly shorter than the control group (P<0.05). Conclusion Mezlocillin combine with probiotics in treatment of pediatric infectious diarrhea can effectively improve the clinical efficacy, speed up the rehabilitation process of children.%目的：分析联合应用美洛西林及微生态制剂治疗小儿感染性腹泻的疗效情况。方法将本院收治的92例感染性腹泻分为两组，对照组应用美洛西林单药治疗，观察组联合应用美洛西林及微生态制剂治疗；比较两组临床总有效率、大便性状及大便次数恢复正常时间。结果观察组临床总有效率达95.7%，高于对照组的82.6%（P＜0.05）。观察组大便性状及大便次数恢复正常时间均短于对照组（P＜0.05）。结论联合应用美洛西林及微生态制剂治疗小儿感染性腹泻可有效提高临床疗效，加快患儿康复进程。
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