Objective To evaluate the clinical efficacy of diabetic nephropathy by Huangkui capsule combined with valsartan. Methods 96 cases of diabetic nephropathy were randomly divided into two groups, 48 cases in each group, control group used valsartan treatment, observation group adopt Huangkui capsule combined with valsartan in the treatment. Results Before treatment, two groups of patients in the TC, TG, SCR and UAER four indexes had no signiifcant difference (P>0.05), after treatment, observe group in the TC, TG, UAER, the three indicators improvement effect was significantly better than the control group (P<0.05) and SCR levels no signiifcant difference (P>0.05). Two groups of patients all did not appear serious adverse reaction (P>0.05). Conclusion Diabetic nephropathy patients take Huangkui capsule combined with valsartan in the treatment effect significantly, can make the blood glucose and renal function in patients with improved, at the same time control the occurrence of adverse reactions.%目的：探讨糖尿病肾病采取黄葵胶囊联合缬沙坦治疗的临床疗效。方法将96例糖尿病肾病患者随机分为两组，各48例；对照组单用缬沙坦治疗，观察组采取黄葵胶囊联合缬沙坦治疗。结果治疗前，两组患者在TC、TG、SCr以及UAER四项指标上差异均无统计学意义（P＞0.05）；治疗后，观察组患者在TC、TG、UAER三项指标改善效果均优于对照组，差异具有统计学意义（P＜0.05），SCr指标水平则差异无统计学意义（P＞0.05）。两组患者均没有出现严重不良反应（P＞0.05）。结论糖尿病肾病患者采取黄葵胶囊联合缬沙坦治疗效果显著，可使患者血糖及肾功能得到有效改善，同时控制不良反应的发生。
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