Objective To improve the quality of life, improve the psychological status and prolong the survival time of the patients with liver cancer and the patients with the liquid quality. Methods Selected April 2010 to October 2014 were 83 cases of hepatocellular carcinoma with cachexia in patients with, for liver cancer patients with cachexia in patients with poor quality of life, lose confidence to the life, given specialist care, basic nursing, psychological nursing and nursing of traditional Chinese medicine and comprehensive nursing and to the families of effective management. Results The quality of life of the patients was significantly improved, the life confidence was increased, the family members could cooperate effectively and the quality of nursing was satisfied. Conclusion The comprehensive nursing intervention on the quality of life of patients with liver cancer and the quality of life of the patients with the quality of life of the patients was improved obviously, the mental state was significantly improved and the survival time of the patients was prolonged.%目的：对肝癌伴恶液质的患者实施综合性护理干预以提高患者生存质量，改善心理状态及延长患者生存时间。方法入选我科2010年4月～2014年10月收治的83例肝癌伴恶液质患者，针对肝癌伴恶液质患者生活质量低下、对生活失去信心，予专科护理、基础护理、心理护理及中医护理等综合护理并对家属进行有效管理。结果患者的生活质量明显改善、生活信心增强，家属能有效配合并对护理质量满意。结论综合护理干预对肝癌伴恶液质患者的生活质量明显提高，心理状态明显改善并有效延长患者生存时间。
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