Objective To investigate the effect of etomidate anesthesia for patients with esophageal varices. Methods 90 cases with esophageal varices were selected from June 2011 to December 2012 in our hospital and were researched and analyzed, these patients were divided into three groups, 30 patients in each group, group Ⅰ was treated with fentanyl and propofol anesthesia, group Ⅱ was given fentanyl and etomidate anesthesia, groupⅢ was given the mixture of fentanyl and propofol etomidate combined anesthesia. The blood pressure, patients before and after drug injection nausea, vomiting, patient satisfaction of three groups were monitored. Results There was no significant difference in blood pressure changes of group Ⅱ and group Ⅲ before and after drug injection (P>0.05); group I patients received drug injections, blood pressure decreased from 15% to 30%, blood pressure before and after the injection had significant difference (P<0.05). Group Ⅲ patients were 100% no response at the time of examination, patient satisfaction was 100%. Conclusion Fentanyl, propofol, etomidate combined anesthesia of patients with esophageal varices accept gastroscopy treatment effect is quite good, can promote the use.%目的：探讨食管静脉曲张患者接受依托咪酯麻醉的效果。方法根据2011年6月～2012年12月我院食管静脉曲张患者90例进行研究分析，将这些患者分成三组，均为30例，Ⅰ组使用芬太尼和丙泊酚麻醉，Ⅱ组使用芬太尼和依托咪酯麻醉，Ⅲ组使用芬太尼和丙泊酚联合依托咪酯混合液麻醉。监测患者接受药物注射前后血压、术后患者恶心、呕吐情况，患者满意度。结果Ⅱ、Ⅲ组患者接受药物注射前和注射后的血压变化不存在统计学差异（P ＞0.05）；Ⅰ组患者接受药物注射后，血压降低了15%～30%，注射前后血压存在统计学差异（P＜0.05），Ⅲ组患者在镜检时100%没有反应，患者满意度为100%。结论芬太尼、丙泊酚、依托咪酯联合麻醉对食管静脉曲张患者接受胃镜治疗的效果比较好，可以推广使用。
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