ObjectiveTo study the effect of Ambroxol and Budesonide aerosol inhalation in treatment of acute exacerbation of chronic bronchitis. MethodsFrom October 2012 to September 2014 in our hospital, 108 cases of patients with acute attack of chronic bronchitis were divided into observation group and control group 54 cases, control group was treated with the conventional synthesis methods, observation group in the control group on the basis of the total ammonia bromine rope, combination treatment with budesonide atomization inhalation, observed and compared the therapeutic effect of two groups.Results The observation group of patients treatment the total effective rate was 94.5%, control group was 85.2%, the observation group is signiifcantly higher than the control group,P<0.05, there was statistically signiifcant. Two groups of patients before treatment temperature, c-reactive protein, white blood cells, blood sedimentation, neutrophils mean no signiifcant difference, decreased after treatment, the decline in observation group is significantly higher than the control group,P<0.05, with statistical significance.ConclusionThe effect of Ambroxol and Budesonide aerosol inhalation in treatment of acute exacerbation of chronic bronchitis safe and stable.%目的：探讨氨溴索、布地奈德雾化吸入联合治疗慢支急性发作的临床疗效。方法选取2012年10月～2014年9月在我院接受治疗的慢支急性发作患者108例，并根据患者具体情况分为观察组和对照组各54例，对照组采用常规综合方法进行治疗，观察组在对照组基础上加用氨溴索、布地奈德雾化吸入联合治疗，观察并比较两组的治疗效果。结果观察组患者治疗总有效率为94.5%，对照组为85.2%，观察组明显高于对照组，P＜0.05，具有统计学意义；治疗前两组患者体温、C反应蛋白、白细胞、血沉、中性粒细胞均值无明显差异，治疗后均下降，下降幅度观察组明显高于对照组，P＜0.05，具有统计学意义。结论氨溴索、布地奈德雾化吸入联合治疗慢支急性发作疗效显著，安全稳定。
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