内皮细胞在凋亡或激活条件下可以释放一种直径为0.05~1的囊泡状物质，我们称其为内皮细胞微粒。在脓毒血症中我们发内皮细胞微粒水平明显升高，这说明内皮细胞微粒与脓毒血症之间存在着一定关系。内皮细胞微粒通过自身表达的物质及刺激其他细胞表达的物质而在炎症、凝血、血管功能改变中产生重要作用。该研究就内皮细胞微粒的形成及与脓毒血症的关系做一概述。%Under apoptosis or activated conditions, the endothelial cells can shed a diameter of 0.05-1vesicle-like substances, named endothelial microparticles (EMPs). It has been documented that the level of EMPs significantly increased in sepsis, which indicated that there is a certain relationship between the EMPs and sepsis. The substances expressed by EMPs and other cells stimulated by EMPs play an important role in inflammation, coagulation, vascular functional changes. This review was written to give an outline about the formation of EMPs and the relationship between EMPs and sepsis.
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