目的：确定男性尖锐湿疣患者疣体和手指人乳头瘤病毒6/11型的感染。方法：采用PCR荧光法对46例男性尖锐湿疣患者疣体和手指进行HPV6/11型核酸定性、定量检测,同时以20名无尖锐湿疣的男性手指作对照。结果：尖锐湿疣患者39例疣体(39/46＝84.78％)阳性,手指25例(25/46＝54.35％)阳性。无尖锐湿疣患者的手指仅2人阳性,差异有显著性意义( P<0.05)。 HPV6/11型疣体病毒载量为6.60×107±3.77×108,病毒载量与病程长短无相关性；尖锐湿疣患者的手指病毒载量为5.72×103±1.75×104,低于疣体的病毒载量(P<0.05)。结论：男性尖锐湿疣患者的手指携带HPV6/11型,其在尖锐湿疣的传播意义有待研究。%Objective:To determine the infection of HPV 6/11 in warts and fingers of male patients with condyloma acuminatum ( CA) . Methods:HPV 6/11 type was detected qualitatively and quantitatively by polymerase chain reaction fluorescence method in warts and fingers in 46 male patients with CA. Twenty men without CA were used as controls. Results: HPV6/1l type was detected in warts in 39 cases ( 39/46=84.78%) and in fingers in 25 cases (25/46=54.35%),while HPV 6/11 type only detected in the fingers in 2 men. There was a significant difference in the detection of HPV 6/11 type in fingers between the CA patients and the controls (P<0.05). The viral load in warts was 6.60×107±3.77×108,and the quantity was not correlated to the duration of infection;The viral load in fingers was 5.72×103 ±1.75×104,which was lower than that detected in warts ( P<0.05) . Conclusions:The fingers in CA patients carry HPV 6/11 type,and the significance in the transmission of CA needs study in future.
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