髋关节暂时性骨质疏松症(transient osteoporosis of the hip,TOH)被归类为骨髓水肿综合征的一种.TOH既往研究不少,对其发病机制存在争议.近年来随着影像学、病理学、分子生物学等多学科的发展,研究发现该病发病机制较复杂且不明确,本文从神经源性、骨坏死、血管功能异常、软骨下骨折、遗传、区域性加速现象等方面对TOH的相关发病机制的研究进展进行了概括.%Transient osteoporosis of the hip(TOH)is classified as a type of bone marrow edema syndrome.TOH is lack of previous study and there is still controversy about his pathogenesis.In recent years,with the development of multi-discipline, such as imaging,pathology,molecular biology,the study has found that the pathological mechanism is complex,while its mech-anism is still not clear,which need further research.This paper summarizes the research progress on the pathogenesis of TOH from neurogenic,osteonecrosis,abnormal vascular function,subchondral fracture,heredity and regional acceleration and son on.
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