目的：初步研究多个低b值DWI技术在心脏检查中的成像技术和成像特点。方法对符合入组和排除条件的已签署知情同意书的30例健康志愿者行3.0T CMR Cine电影、T2WI和多b值DWI序列扫描，探讨此序列临床应用的可行性，统计分析心肌在各节段、不同供血区、年龄和性别中有无差异，并讨论行DWI序列扫描时，选择何种b值能够更好地反映心肌血流灌注情况。结果当b=20、60 s/mm2时，图像质量较好。健康志愿者各节段心肌ADC值不全相等（F=6.315，P<0.001）。左前降支供血区，右冠状动脉供血区和左旋支供血区ADC值有差异（F=27.804，P＜0.001），分别为（0.01186±0.00422）mm2/s，（0.01032±0.00333）mm2/s和（0.00902±0.00248）mm2/s。从基底部到心尖部，心肌平均ADC值无差异。结论多个低b值DWI技术在CMR检查中具有较好的可行性和可重复性。健康志愿者各节段心肌ADC值存在节段性差异。当b=20，60 s/mm2（<100 s/mm2）时，图像质量较好，可能提示此DWI图像可更好地显示心肌血流灌注特点，为今后选择合理b值进行相关研究提供参考。%Objective To investigate the imaging technology and characteristics of cardiac magnetic resonance (CMR) multi-low-b DWI technology.Methods With a 3.0T magnetic resonance imaging (MRI) system, cardiovascular magnetic imaging, including MR Cine, T2WI and multi-low-b DWI technology, was performed in 30 healthy volunteers who had given written informed consent to investigate the clinical feasibility of multi-low-b DWI technology and to explore whether ADC values in different segmental myocardium, differentblood supply areas, different age-groups and gender were similar or not. A discussion was made on whichb value shouldbe selected tobetter relfect the perfusion of myocardium when using DWI technology to scan cardiac structure.Results The image quality of multi-low-b DWI technology wasbetter when theb values were 20, 60 s/mm2 (b<100 s/mm2). The study showed ADC values of some myocardial segments in healthy volunteers were different (F=6.315,P<0.001). ADC values of differentblood supply areas were different (F=27.804,P<0.001) asbelow: the ADC value of the left anterior descendingbranch was (0.01186±0.00422) mm2/s; the ADC value of the right coronary artery was (0.01032±0.00333) mm2/s; the ADC value of the left circumlfex was (0.00902±0.00248) mm2/s. Besides, myocardial ADC values were not different frombase to apex.Conclusion The CMR multi-low-b DWI technology is feasible and repeatable. Myocardial ADC values have regional variation. The image quality isbetter when theb values are 20, 60 s/mm2 (b<100 s/mm2) which indicates the images obtained through DWI technology canbetter relfect myocardial perfusion. The research provides relevant reference for choosing the appropriateb values in the future studies.
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