目的:探讨1.5T磁共振扩散加权成像(DWI)及表观扩散系数(ADC)对子宫内膜癌的诊断及鉴别诊断的临床应用价值.方法:选取37例临床病理证实为子宫内膜癌病例资料、11例良性内膜病变病例资料,另选20名正常志愿者资料,将其分为子宫内膜癌组、子宫内膜良性病变组以及对照组(志愿者),回顾性对比分析3组1.5T MR DWI及常规MRI图像;比较总结各组病变DWI图像特性,分析各组间以及子宫内膜癌组内不同病理分型ADC值的差异.结果:不同性质子宫内膜病变组的DWI信号有一定特点.子宫内膜癌组、良性病变组以及对照组组间平均ADC值差异存在统计学意义,子宫内膜癌组内平均ADC值差异无统计学意义.结论:DWI与ADC值对检出子宫内膜病变非常敏感,ADC值有助于子宫内膜癌的鉴别诊断,DWl结合常规MRI序列可为临床早期治疗提供可靠的诊断依据.%Objective:To discuss the applicative value of 1.5TMR-diffusion weighted imaging (DWI) sequence and apparent diffusion coefficient (ADC) measurement in the diagnosis and differential diagnosis of endometrial carcinoma.Methods: Thirty seven cases were collected in endometrial carcinoma group, 11 cases were selected in benign group and other 20 normal volunteers. Data of the DWI and ADC value, common-MRI(c-MRI) sequence in the 48 patients and 20 normal volunteers was contrasted and analyzed.Results: The differences between endometrial malignant tumors, benign lesions and the normal have statistical significance.Conclusion: 1.5 T MR-DWI sequence and ADC value has a superior ability in detecting endometrial lesions. It can be used to differentiate the endometrial carcinoma from either benign or normal cases, it can provide reliable assistance in the clinical cure.
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