目的 比较Tecnis ZCB00非球面人工晶状体(IOL)和球面AR40e IOL植入术后的视觉质量.方法 选取2015年1～7月在保定市第一中心医院接受治疗的白内障患者60例(60眼).按随机数字表法将其分为观察组与对照组,每组各30例.两组患者均行超声乳化白内障吸除联合IOL植入术,观察组植入ZCB00 IOL,对照组植入AR40e IOL.术后3个月观察患者的裸眼视力、最佳矫正视力(BCVA)、对比敏感度(CSr)及5 mm瞳孔直径下的全眼及内眼像差及调制传递函数(MTF).结果 两组患者的裸眼视力及BCVA比较,差异无统计学意义(P＞0.05).在5 mm瞳孔直径下,观察组术后全眼及眼内高阶像差均低于对照组,差异有高度统计学意义(P＜0.01).在明视(6、12、18cpd)、明视加眩光(除1.5 cpd)、暗视(1.5、6、12 cpd)及暗视加眩光所有空间频率下,观察组CSF值优于对照组,差异有统计学意义(P＜0.05).观察组在5 mm瞳孔直径下MTF值(除30 cpd)均高于对照组(P＜0.05).结论 与传统球面IOL比较,植入负球差设计的非球面IOL可以显著减少IOL眼的总球差,改善白内障患者术后的视觉质量.%Objective To compare the impact on functional vision of the aspheric Tecnis ZCB00 lens with the spherical Sensar AR40e lens.Methods From January to July in 2015,60 patients with cataract in the First Central Hospital of Baoding were selected and divided into observation group and control group according to random number table,with 30 cases in each group.All cataract patients underwent phacoemulsification were randomized to receive an aspheric IOL (AMO Tecnis ZCB00,as observation group) or a spherical IOL (AMO AR40e,as control group).Uncorrected visual acuity,best corrected visual acuity (BCVA),contrast sensitivity function (CSF),spherical aberration of the whole eye and internal optics (IOL) at 5 mm pupil diameter and modulation transfer function(MTF) were examined 3 months after postoperatively.Results The postoperative visual activity was not significantly different between the two groups (P ＞ 0.05).The postoperative high order aberration of the eye at 5 mm pupil diameter in the observation group was less than that in the control group (P ＜ 0.01).In the bulk of spatial frequencies,including photopic vision (6,12,18 cpd),photopic vision with glare conditions (except 1.5 cpd),scotopic vision (1.5,6,12 cpd) and scotopic vision with glare,mean CSF generally in the observation group was higher than that in the control group,with statistical significance (P ＜ 0.05).The values of MTF in the observation group were higher than those in the control group except 30 cpd in 5.0 mm pupil sizes (P ＜ 0.05).Conclusion Comparing to the conventional spherical IOL,the negative aspheric IOL may reduce the spherical aberration and improve visual performance of pseudophakic eyes.
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