Objective To explore the clinical efficacy of early enteral nutrition after total gastrectomy for gastric cancer patients. Methods From September 2006 to June 2011, 73 patients were treated with total gastrectomy for gastric cancer in general surgery in our hospital and randomly divided into EEN group (38 cases) and TPN group (35 cases).The patients of EEN group was given early gastrointestinal feeding with tube enteral nutrition, and the patients of TPN group was gvien parenteral nutrition from intravenous. The nutrition indicators, liver function and postoperative recovery of patients before treatment and one week after treatment were observed. Results One week after surgery, two groups of patients with body weight, TP and Alb did not change significantly compared with the preoperation, without significant differences (P > 0.05). Indicators of liver function in patients with TPN group was significantly higher than the EEN group of patients, with statistically significant difference (P < 0.05). EEN group of patients in the postoperative ventilation time, into the liquid diet in time and hospital stay of patients were less than the TPN group, with statistically significant differences (P < 0.05). Conclusion EEN and TPN after total gastrectomy can be used as a nutritional support method, EEN is more safety and tolerability.%目的 探讨因胃癌行全胃切除的患者术后早期肠内营养的临床疗效.方法 我院普外科于2006年9月～2011年6月共收治因胃癌行全胃切除术的患者73例,将其随机分为早期肠内营养组(EEN组)及全肠外营养组(TPN组),分别为38例和35例患者.EEN组经胃肠营养管早期给予肠内营养,TPN组经静脉给予肠外营养.观察患者治疗前及治疗后1周营养指标、肝功及术后恢复情况.结果 术后1周,两组患者体重、血清总蛋白(TP)及白蛋白(Alb)同术前变化不明显,差异无统计学意义(P ＞ 0.05);TPN组患者各项肝功指标较显著高于EEN组患者,差异有统计学意义(P ＜ 0.05);EEN组患者在术后通气时间、进流质饮食时间及住院天数方面要少于TPN组患者,差异有统计学意义(P ＜ 0.05).结论 TPN及EEN均可作为全胃切除术后的营养支持方式,EEN更具安全性和耐受性.
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