Objective To explore the effect of cognitive behavior intervention combined with antidepressant treatment on sleep and life quality in depression patients. Methods 120 cases of patients with depression were divided into control group and observation group with 60 patients each group. The control group were given simple oral Citaloparm treatment and the observation group received cognitive behavior intervention combined with Citaloparm treatment. Hamilton depression scale (HAMD), pittsburgh sleep quality index (PSQI), quality of life questionnaire (GQOLI-74) were used to evaluate depression status, sleep and life quality before and 4, 8 weeks after treatment. Results HAMD and PSQI scores greatly decreased 4 and 8 weeks after treatment in the two groups, and which were much lower in the observation group than the control group (P < 0.05); GQOLI score was much higher in the observation group than that in the control group after treatment (P < 0.05). Conclusion Compared with single antidepressant treatment, cognitive behavior intervention combined with antidepressant treatment can greatly improve depression status, sleep and life quality of patients.%目的 探讨抗抑郁剂联合认知行为治疗对抑郁症患者睡眠及生活质量的影响.方法 将120例抑郁症患者随机分入对照组与观察组,每组各60例.对照组患者给予单纯口服西酞普兰治疗,观察组患者在西酞普兰口服基础上接受认知行为治疗.干预前、干预后4周及8周采用汉密尔顿抑郁量表(HAMD)、匹兹堡睡眠质量指数(PSQI)、生活质量综合评定问卷(GQOLI-74)评价比较两组抑郁状态、睡眠及生活质量.结果 治疗后4周及8周,两组HAMD评分及PSQI均明显下降(P<0.05),且观察组显著低于对照组(P<0.05);观察组GQOLI总分显著高于对照组(P<0.05).结论 相对于单纯抗抑郁剂治疗,抗抑郁剂联合认知行为治疗可显著改善患者抑郁状态,提高睡眠及生活质量.
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