目的 评估北京地区部分医院感染(院感)和死亡的关系,分析医院感染的发生现状,为临床对院感的防治提供理论依据和方法.方法研究对象主要来自于北京10家医院,对入院时间超过48 h的死亡患者进行病历资料的调查和死亡分析,其中,医院感染与患者死亡之间的相关性由临床医生和院感专业控制人员做出诊断.结果共对1 945例符合要求的死亡患者进行了研究,其中,518例(26.6%)患者死亡时发现有医院感染,与医院感染相关的死亡患者有285例(14.6%),6.6%的死亡患者与医院感染有明确的相关性,8.0%的死亡患者可能与医院感染有关.在所有死亡患者中,医院感染的影响占了2.8%,多见于呼吸道(39.0%)、尿道(19.0%)、血液(16.9%)和胃肠道、腹腔(6.6%).结论医院感染引起的死亡比80年代明显降底,为了进一步提高人群的健康水平,需要对引起致死性医院感染的原因进一步研究.%Objective To evaluate the relationship between nosocomial infection (NI) and inpatients death in Beijing area hospital, analyze the occurrence status of NI, in order to provide theory basis and method for prevention and treatment of NI in clinic. Methods A multicentre descriptive study was conducted in 10 hospitals of Beijing. Medical records of consecutive patients who died after admission at least 48 h were investigated and the cause of death was analyzed. The contribution of NI to death was assessed by clinical physicians and professional control personnel of NI. Results 1 945 cases of patients who meet the demand were analyzed, among whom 518 cases (26.6%) had NI, the death of 285 cases (14.6%) were related to NI, 6.6% death patients were specific related to NI, and 8.0% death patients were possible related to NI. Among all death patients, NI was accounted for 2.8%. Infections of lower respiratory tract, urinary canal, blood and gastrointestinal tract were accounted for 39.0%, 19.0%, 16.9% and 6.6% among all NI in patients. Conclusion The death caused by NI was lower than eighties. Further research of death reasons caused by NI is needed, in order to further improve the level of people's health.
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