Vascular endothelial dysfunction is a main factor causing cardiovascular disease like atherosclerosis, etc.. Maintain integrity of vascular endothelial structure and function is a premise to effectively protect endothelial cells and restore their injured functions. Therefore, in recent years multi-link and multi-target protection of endothelial cells has become a key point in research. Compound herbal formulae based on relatively complex composition have unique advantage on exerting drug efficacy in multi-target way. Danhong Injection as a kind of herbal compound preparation has role in protecting vascular endothelial function according to basic and clinical research. The article makes a review of Danhong Injection's endothelial injure protection in the aspects of anti-inflammatory, anti-thrombosis, and antioxidant in order to provide new ideas for prevention and treatment of atherosclerosis and other cardiovascular diseases by compound herbal formula.%血管内皮功能障碍是导致动脉粥样硬化等心血管疾病发生的重要因素,保持血管内皮结构与功能完整性是有效保护内皮细胞、恢复受损内皮功能的前提,因此对内皮细胞多环节、多靶点保护成为近年来研究关键.而中药复方基于组方相对复杂性,在多靶点发挥药物疗效方面显现独特优势.丹红注射液作为中药复方制剂,基础及临床研究提示其对血管内皮功能具有保护作用.本文从抗炎、抗血栓、抗氧化作用等方面对丹红注射液的内皮损伤保护作用作一综述,为中药复方对动脉粥样硬化等心血管疾病的防治提供新的思路.
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