Cervical intraepithelial neoplasia of grade I (CIN I for short) is the common precancerous lesions of cervical cancer in gynaecology department, and it closely relates to infection of human papilloma virus. However, because of the uneven technology of pathology physicians and colposcopy physicians, and the restriction of colposcopy itself, the consistency of CIN I diagnosis has difference, and the treatment of CIN I also has controversy. In order to avoid over-treatment and undertreatment of CIN I , many scholars struggle to find out an accurate biological index to forecast the development trend of CIN I . This paper summarizes the basic research and clinical treatment status of CIN I .%宫颈上皮内瘤变Ⅰ级简称为CINⅠ,是妇科常见的宫颈癌前病变,与人乳头瘤病毒感染密切相关.然而由于病理科医师、阴道镜检查医师的技术参差不齐及阴道镜本身的制约,CINⅠ诊断的一致性存在差异,且CINⅠ的治疗至今仍存在争议.为了避免CINⅠ的过度治疗与治疗不足,许多学者不懈努力以期寻找到一个准确的生物学指标预测CINⅠ的发展趋势.本文就CINⅠ的基础研究与临床治疗现状进行综述.
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