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迟发性脑血管痉挛的临床特点与治疗

         

摘要

Objective: To explore the efficacy of the clinical treatment for the delayed cerebral vasospasm. Methods: The clinical data of 42 patients with delayed cerebral vasospasm in our hospital from March 2006 to February 2010 were retrospectively analyzed. Results: After treatment, patients were symptom relief after 1 week, 2 weeks mitigation of meningeal irritation, 4 weeks normal cerebrospinal fluid, after 1 month CT normal, then bleeding and complications in the treatment group were better than those of the control group (ρ<0.05, ρ<0.01). In addition, SAH and DCVS were the main causes of intracranial aneurysm rupture. And the location and size of the aneurysm was no significant relationship. DCVS occurrence was no relationship with the age and sex. Conclusion: The existence of the base pool is to produce clot direct cause of DCVS. Nimodipine treatment of delayed cerebral vasospasm has significant effect.%目的:探讨迟发脑血管痉挛的临床治疗效果.方法:回顾性分析我院2006年3月~2010年2月收治入院的迟发性脑血管痉挛患者42例的临床资料.结果:治疗组患者经治疗后1周后症状减轻、2周脑膜刺激征缓解、4周脑脊液正常、1个月后头颅CT正常、再出血及并发症等均优于对照组(P<0.05,P<0.01);另外,SAH并DCVS的主要病因是颅内动脉瘤破裂,与动脉瘤的部位及大小无明显关系,DCVS的发生与年龄、性别无关.结论:基底池中凝血块的存在是产生DCVS的直接原因.尼莫地平治疗迟发性脑血管痉挛的疗效显著.

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