Objective: To determine the characteristics of gastric residuals in very low birth weight infants (VLBW) with necrotizing enterocolitis (NEC) and evaluate the role of gastric residuals in early identification of NEC. Methods: In a case-control study, 30 NEC patients were matched with control infants by birth weight, gestalional age. sex and were born from September 2008 to September 2010 in our department. Feeding characteristics were recorded from birth to the days at diagnosis of NEC in both groups, and the data in the two groups were compared. Results: Mean maximum residual from birth to NEC onset (5.35±2.14) ml was significantly higher in patients than that in control infants (2.38±2.72) ml, and maximum residual as percentage of the corresponding feed volume was also higher in patient (42.10±14.65)％ than that in the control infants (21.30±7.51)％ (P＜0.05). The percentage of infants with hemorrhagic residuals in patients (63.33％) was significantly higher than in control infants (26.67％) (P＜0.05). Conclusion: Gastric residuals seem to be the best predictor for NEC because Gastric residuals.%目的:研究极低出生体重儿坏死性小肠结肠炎(NEC)中胃潴留的特征,探讨胃潴留在NEC早期诊断中的意义.方法:选取2008年9月～2010年9月我科住院治疗的NEC患儿30例,同期住院的患儿按出生体重、性别、胎龄相当的非NEC患儿30例为对照组配对.记录NEC组患儿出生到确诊当日,胃潴留的液量以及性质的变化,对照组患儿在相同时间段亦进行相应的记录.比较两组间的差异.结果:NEC组胃潴留最大量(5.35±2.14)ml显著高于对照组的(2.38±2.72)ml,以及潴留量所占前次喂养量的最大比率(42.10±14.65)%亦高于对照组的(21.30±7.51)%,差异均有统计学意义(均P＜0.05);NEC组出血性胃潴留的比例(63.33%)亦显著高于对照组(26.67%)(P＜0.05).结论:NEC患儿胃潴留明显增加,且易出现出血性胃潴留,提示胃潴留的监测在早期诊断NEC中起着重要的作用.
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