Objective: To explore the clinical efficacy of gastric cancer treated and prevented by surgery combined 125I implantation. Methods: 53 cases of patients with advanced gastric cancer were divided into two groups, group A of 28 cases treated by surgery combined 125I implantation, group B of 25 cases by routine surgery. Results: 1, 2, 3-year of local recurrence rates of group A were 7.1％, 17.9％, 35.7％ respectively, survival rates of group A were 92.9％, 71.4％, 46.4％ respectively. 1, 2, 3-year of local recurrence rates of group B were 20.0％, 48.0％, 72.0％ respectively, survival rates of group B were 80.0％, 56.0％, 20.0％ respecuvely. Conclusion: Surgery combined 125I implantation for the treatment of advanced gastric cancer can be better control of tumor recurrence and metastasis and prolong Survival, and fewer complications, effective security, is an effective treatment method.%目的:探讨术中植入125I粒子治疗及预防胃癌复发转移的临床疗效.方法:共选取53例中晚期胃癌患者,分为两组,A组28例行手术联合125I粒子植入治疗,B组25例行常规手术治疗作为对照.结果:A组患者1、2、3年的局部复发转移率分别为7.1%、17.9%、35.7%,生存率分别为92.9%、71.4%、46.4%.B组患者1、2、3年的局部复发转移率分别为20.0%、48.0%、72.0%,生存率分别为80.0%、56.0%、20.0%.结论:手术联合125I粒子植入治疗中晚期胃癌可较好地控制肿瘤局部复发及转移、延长生存期,且并发症少是一种安全、有效的治疗方法.
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