Objective: To evaluate the efficiency and security of Propess (Dinoprostoue) to induce labor in term pregnancies. Methods: We adopted the function of Oxytocin and Propess comparatively, 90 cases of Propess and 60 cases of Oxytocin were studied. Their efficiency to promote the ripeness of cervix and the influence on the birth process for the 150 cases of low cervical scale of term pregnancies. Results: Propess could raise the Bishop cervical scale by (2.76±1.01) scores, the efficiency to promote the ripeness of cervix could reach 88.89%, the parturient time was (19.8±10.1) hours, the total labor stages were (6.8±3.1) hours, the rate of cesarean operatiou dropped to 16.67%. The deviance with Oxytocin had obvious statistical significance. The clinical usage of Propess and Oxytocin had no serious adverse reactions. Conclusion: Propess (Dinoprostone) is an effective drug to promote the ripeness of cervix and induce labor. It is convenient, safe and reliable.%目的:评价普贝生(地诺前列酮)对足月孕妇引产的效果和安全性.方法:采用普贝生与缩宫素临床对比,普贝生治疗90例,缩官素治疗60例,观察其对150例足月宫颈低评分孕妇促宫颈成熟的有效性和对产程的影响.结果:普贝生能提高宫颈Bishop评分(2.76±1.01)分,促宫颈成熟效果达88.89%,临产时间为(19.8±10.1)h,总产程(6.8±3.1)h,剖宫产率降至16.67%,与缩宫素比较,差异有明显的统计学意义.普贝生和缩宫素临床使用均无严重不良反应.结论:普贝生(地诺前列酮)是一种有效的促官颈成熟和引产药物,使用方便,安全可靠.
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