目的：研究拉西地平联合贝那普利对糖尿病合并高血压患者血压及血脂水平的影响。方法选取2013年5月～2014年5月我院收治的76例糖尿病合并高血压患者，将其随机分成治疗组与对照组，各38例。治疗组采用拉西地平联合贝那普利进行治疗，对照组采用拉西地平进行治疗，连续治疗4周。对两组患者的治疗效果进行对比分析。结果治疗后，治疗组的偶测与24h平均收缩压和舒张压显著低于对照组，两组结果具有显著差异（P＜0.05）；治疗后，治疗组的空腹血糖、Fib、HbAC比值显著低于对照组，治疗组的HDL-C显著高于对照组，两组结果具有显著差异（P＜0.05）。结论对糖尿病合并高血压的患者采用拉西地平联合贝那普利进行治疗，可以明显降低患者的血压，维持了患者血糖的正常水平，且轻微升高了患者的HDL-C，具有抗氧化及抗动脉粥样硬化作用，值得临床推广与应用。%Objective To explore the influence of Lacidipine combined with Benazepril to blood pressure and blood lipid levels of diabetic patients with hypertension. Methods 76 cases of diabetic patients with hypertension cured in our hospital from May 2013 to May 2014 were selected and randomly divided into therapy group and control group with 38 cases in each. Patients in therapy group were treated with Lacidipine combined with Benazepril, and patients in control group were treated with Lacidipine, continuous treatment for 4 weeks. Treatment effects of the two groups were compared. Results After the treatment, even measured,24h average systolic and diastolic of therapy group were significantly lower than those of control group, and the results of the two groups were significantly different (P<0.05).After the treatment, fasting blood glucose, Fib, HbAC ratio of therapy group were significantly lower than those of control group, HDL-C of therapy group was significantly higher than that of control group, and the results of the two groups were significantly different(P<0.05). Conclusion Lacidipine combined with Benazepril in treatment of diabetic patients with hypertension can significantly reduce the patient’s blood pressure,maintain the normal level of blood glucose in patients,and slightly elevate HDL-C of patients.It has anti oxidation and anti-atherosclerosis effect. It is worthy of clinical popularization and application.
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