目的：探讨循证药学在抗生素治疗方案中的应用及其临床实践效果。方法选择来我院就诊的上呼吸道感染患者84例，随机分为观察组与对照组各42例。对照组患者服用红霉素肠溶胶囊治疗；观察组患者按照循证药学的方法，采用青霉素钠注射方式进行治疗。比较两组患者的治疗效果。结果两组治疗第3、5、7天，观察组有效例数为19、28、38例；对照组有效例数为8、17、26例。观察组治疗效果与对照组相比，差异有统计学意义（P＜0.05），比较两组患者用药的不良反应，两组患者的血常规、尿常规及肾脏功能均未出现异常，差异无统计学意义（P＞0.05）。结论遵照循证药学的方法对呼吸道感染患者给予治疗，效果更明显。%Objective To explore the application of evidence-based medicine in the antibiotic treatment effect and clinical practice.Methods 84 cases of patients with upper respiratory tract infection in were selected and randomly divided into observation group and control group, each of 42 cases. The control group was treated with erythromycin enteric capsules treatment, and observation group was treated with penicillin sodium injection methods, in accordance with the method of evidence-based medicine. The therapeutic effects of two groups were compared. Results In the treatment of third, fifth, seventh days, the observation group was 19, 28, 38 cases, the control group was 8, 17, 26 cases. The effect of observation group was significantly different from the control group (P<0.05). The adverse reactions of the patients in treatment group, blood routine, urine routine and renal function of two groups were normal, the differences were not statistically significant (P>0.05).ConclusionThe effect of evidence-based medicine in the treatment of patients with respiratory tract infection is more obvious.
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