Objective To analyze the clinical application value of misoprostol combined mifepristone on induced abortion of second trimester pregnancy in patients with scar uterus.Methods 120 patients with scar uterus of induced abortion on second trimester pregnancy, who were received and treated in our hospital from April 2013 to April 2015, were selected and were divided into two groups. To comparative analyze the success rate and effect of induced abortion between control group which was treated with induced abortion by ethacridine intra-amniotic injection, and observation group which was treated with induced abortion by misoprostol combined mifepristone. Results The success rate of induced abortion in observation group was significantly higher than which in control group, the difference was statically significant(P<0.05). The residual rate of clinical placenta and the incidence of soft birth canal laceration in observation group were significantly lower than which in control group, the differences were statically significant(P<0.05).ConclusionMisoprostol combined mifepristone on induced abortion of second trimester pregnancy in patients with scar uterus has important application value, could obviously improve the success rate of induced abortion, could reduce patients’ clinical complication rate, could improve the induced abortion safety of patients, is worthy of popularization and application.%目的：分析米索前列醇联合米非司酮在瘢痕子宫中期妊娠人工流产中的应用价值。方法选取我院2013年4月~2015年4月接收并治疗的120例瘢痕子宫中期妊娠人工流产患者，将其分为两组，对照组患者采用依沙吖啶羊膜腔内注射人工流产，观察组患者采用米非司酮联合米索前列醇人工流产，分析两组患者的人工流产成功率及人工流产效果。结果和对照组相比，观察组患者的人工流产成功率显著偏高，差异有统计学意义（P＜0.05）；观察组患者的临床胎盘残留率及软产道裂伤发生率均显著低于对照组，差异有统计学意义（P＜0.05）。结论米索前列醇联合米非司酮在瘢痕子宫中期妊娠人工流产中具有重要应用价值，能够显著提高患者人工流产成功率，降低患者的临床并发症发生率，提高患者人工流产安全性，值得推广应用。
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