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Current Status of ADSCs-Enriched Fat Grafts in Plastic Surgery

         

摘要

Autologous fat grafting is an increasingly popular technique in plastic surgery for volume augmentation and rejuvenation.However,the unpredictability of long-term volume retention limits its clinical application.Various animal studies have documented the positive effects of adipose tissue-derived stem cells(ADSCs)on the acceleration of lipofilling.However,the results have been inconsistent,and there is an insufficient number of high-quality clinical studies to formulate evidence-based recommendations for ADSC-enriched fat grafts.Moreover,related technical standards,such as the final count of harvested ADSCs and the enrichment ratio,have not yet been established.This systematic review included all clinical trials on ADSC-enriched fat grafts in plastic surgery from PubMed in the past 10 years,as well as all registered clinical trials on ClinicalTrials.Gov.To examine the current landscape of ADSCs harvest,we summarize the current applications of ADSCs in the field of plastic surgery and discuss the current barriers to universal clinical use.

著录项

  • 来源
    《中国整形与重建外科(英文)》 |2020年第4期|P.263-276|共14页
  • 作者单位

    Department of Plastic Surgery Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu 221002 ChinaDepartment of Burn Surgery Changhai Hospital Naval Medical University Shanghai 200433 China;

    Department of Plastic Surgery Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu 221002 China;

    Department of Plastic Surgery Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu 221002 ChinaDepartment of Plastic Surgery The First People’s Hospital of Xuzhou Xuzhou Jiangsu 221002 China;

    Department of Plastic Surgery Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu 221002 ChinaDepartment of Plastic Surgery Zibo Women&Children Hospital Zibo Shandong 255029 China;

    Department of Plastic Surgery Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu 221002 ChinaDepartment of Burn Surgery The First People’s Hospital of Xuzhou Xuzhou Jiangsu 221002 China;

    Department of Plastic Surgery Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu 221002 China;

    Department of Plastic Surgery Affiliated Hospital of Xuzhou Medical University Xuzhou Jiangsu 221002 China;

  • 原文格式 PDF
  • 正文语种 chi
  • 中图分类 人体形态学;
  • 关键词

    Adipose tissue-derived stem cells; Stromal vascular fraction; Fat graft; Cell-assisted lipotransfer; Plastic surgery;

    机译:脂肪组织衍生的干细胞;基质血管分数;脂肪移植物;细胞辅助Lipotransfer;整形手术;
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