目的 探讨胃丛状纤维黏液瘤(PF)的临床病理特征.方法 对1例胃PF患者进行组织学观察及免疫组化染色, 结合文献讨论其临床病理特点及鉴别诊断.结果 胃PF胃镜下主要表现为息肉状或隆起性肿物;组织学特征为肿瘤呈多结节状生长, 瘤细胞梭形, 间质富含小的薄壁血管和黏液样基质, 核呈短梭形或卵圆形.免疫组化示肿瘤细胞Vim、SMA强阳性, CD10局灶弱阳性.结论 胃PF是一种罕见的良性间叶性肿瘤, 诊断需与胃肠道间质瘤、侵袭性纤维瘤等间叶性肿瘤鉴别.%Objective To investigate clinical pathological characteristics of plexiform fibromyxoma (PF) of stomach.Methods Histological observation and immumohistochemical staining were taken in 1 patient with PF of stomach. Its clinical pathological characteristics and differential diagnosis were investigated in combination with literature.Results PF of stomach showed main gastroscopic manifestations as polypoidal or intumescentneoplasm. Its histological characteristics included multiple nodular tumor, fusiform oncocyte, mesenchyme with small thin-walled vessels and myxoid stroma, and short fusiform or oval nucleus. Immunohistochemistry showed oncocyte with strong positive Vim, SMA and weak positive CD10 lesion.Conclusion As a rare benign mesenchymal tumor, PF of stomach requires distinguishing diagnosis from gastrointestinal stromal tumor and aggressive fibromatosis.
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