目的：探讨非营养性吸吮联合开塞露灌肠对极低出生体重早产儿胃肠功能的影响。方法80例极低出生体重早产儿为研究对象，随机分为对照组(38例)，观察组(42例)。两组患儿均给予常规治疗，观察组在此基础上加用非营养性吸吮联合开塞露灌肠治疗，比较两组患儿出生时一般情况，恢复出生体重的时间、留置胃管时间、达全肠道喂养时间、胎便排尽时间、住院时间。结果观察组恢复出生体重时间、留置胃管时间、达全肠道喂养时间、胎便排尽时间以及住院时间均短于对照组[(6.83±1.48)d VS (9.13±1.64)d、(17.50±3.98)d VS (22.45±4.48)d、(37.57±4.34)d VS (44.03±5.89)d、(20.81±2.18)d VS (24.13±2.99)d、(49.55±7.16)d VS (56.12±5.55)d]，两组比较，差异均有统计学意义(P<0.05)。结论非营养性吸吮联合开塞露灌肠可提高极低出生体重早产儿胃肠动力，促进胃肠功能成熟，减少胃管喂养时间，增加体重，缩短住院时间，减少治疗费用，值得临床推广应用。%Objective To investigate influence by non-nutritive sucking combined with glycerol enema on gastrointestinal function in very low birth weight premature infant. Methods A total of 80 very low birth weight premature infants as study subjects were randomly divided into control group (38 cases) and observation group (42 cases). Both groups received conventional therapy, and the observation group received additional non-nutritive sucking combined with glycerol enema for treatment. General delivery time, birth weight recovery time, gastric intubation time, full enteral feeding time, meconium defecation time, and hospital stay were compared between the two groups. Results The observation group had much shorter birth weight recovery time, gastric intubation time, full enteral feeding time, meconium defecation time, and hospital stay than the control group [(6.83±1.48) d VS (9.13±1.64) d, (17.50±3.98) d VS (22.45±4.48) d, (37.57±4.34) d VS (44.03±5.89) d, (20.81±2.18) d VS (24.13±2.99) d, (49.55±7.16) d VS (56.12±5.55) d]. The differences between the two groups all had statistical significance (P<0.05). Conclusion Implement of non-nutritive sucking combined with glycerol enema can remarkably improve gastrointestinal function in very low birth weight infant. It also accelerates gastrointestinal function development, reduces stomach tube feeding time, increases body weight, and shortens hospitalization time and treatment cost. This method is worth clinical promotion and application.
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