近年来，多原发肺癌（ MPLC）的发病率逐渐上升，但目前尚无诊断MPLC的金标准，尤其当多发病灶病理类型相同时，与肺内转移癌的鉴别仍较困难。因此需综合考虑组织学类型、影像学特征、临床表现及分子遗传学特点。新诊断技术的出现为MPLC的正确诊断作了重要补充。 MPLC应将多发病灶单独分期，治疗以手术为首选，预后较好。本文通过总结最新的文献进展，结合本院对MPLC的诊治体会作如下综述。%Recently, the incidence of multiple primary lung cancer( MPLC) is increasing. However, there is a lack of stand-ard diagnostic criteria for MPLC. It is difficult to distinguish MPLC from pulmonary metastasis, especially when the same pathologic type of multiple lesions exists. Therefore, pathologic type, imaging features, clinical manifestations and molecular genetic characteristics should be considered. The emergences of new diagnostic techniques are an important supplement to the diagnosis of MPLC. Each lesion should be staged separately. Surgery should be the preferred treatment option with good prognosis. In this article, we make a review through summarizing the latest literature progress combined with our experience of the diagnosis and treatment for MPLC.
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