Nutrition and health in pregnancy related to the maternal growth and development of the fetus and the health status after birth. Caffeine is one of the frequently contacted food and pharmaceutical compositions in everyday life,its safety in pregnancy had attracted wide attention. In this article,we summarized the results of domestic and oversea clinical researches in recent years,and finally concluded that a large quantity of caffeine intake could lead to adverse pregnancy outcomes such as low birth weight,abortion. Therefore,pregnant women should reduce caffeine intake,but not completely prohibit.%妊娠期的营养与健康关系到胎儿在母体生长发育与出生后的健康状况，而咖啡因作为日常生活中频繁接触的食品和药品成分，其妊娠期使用的安全性已引起广泛的关注。本文通过总结国内外近年来临床研究结果，最终认为大量咖啡因的摄入可能导致低出生体质量儿、流产等不良妊娠结局，因此建议妊娠后减少咖啡因的摄入，但不必完全禁止。
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