Objective To make a quantitative evaluation on the effect of tea catechins on obesity in adults. Methods Computer -based retrieval was made on Cochrane,PubMed,EMBase,CNKI,CBMdisc,VIP,Wanfang database. The searching time range was set from database establishment to 2013. We retrieved literatures which included RCT studies where the trial group was administrated with beverage,pills or capsule containing high - dose tea catechins and the control group was administrated with placebo control,drink control or low-dose tea catechins. The included literatures were made with quality assessment and data extraction. Statistic software was employed on the analysis of body mass,BMI,body fat rate and waistline. Results A total of 25 pieces of literature were included,and 29 RCT studies were extracted,concerning with 2 191 patients, among which 1 187 were in trial group and 1 004 were in control group. Of the 29 RCT studies,there were 22 high-quality(≥4) studies and 7 low-quality( <4) studies. The meta analysis showed that trial group was lower than control group in body mass,BMI,body fat rate and waistline〔MD= -0. 89,95%CI( -1. 46,-0. 32),P=0. 002;MD= -0. 32,95%CI ( -0. 56, - 0. 09),P = 0. 007;MD = - 0. 75,95% CI( - 1. 27, - 0. 24),P = 0. 004;MD = - 0. 66,95% CI ( -1. 24,-0. 07),P =0. 03〕;the subgroup analysis showed that trial group(mixture of tea catechins and caffeine)was lower than control group( caffeine) in body mass,BMI,body fat rate and waistline〔MD = -0. 97,95%CI( -1. 31,-0. 64),P< 0. 001;MD = - 0. 40,95% CI( - 0. 54, - 0. 26),P < 0. 001;MD = - 0. 90,95% CI( - 1. 39,-0. 42),P=0. 0003;MD = -1. 16,95%CI( -1. 99,-0. 34),P =0. 006〕;trial group( Asian) was lower than control group in body mass,BMI,body fat rate and waistline〔MD= -1. 01,95%CI( -1. 63,-0. 38),P=0. 002;MD= -0. 41,95%CI( -0. 67,-0. 16),P =0. 002;MD = -1. 21,95%CI( -1. 86,-0. 57),P =0. 0002;MD =-0. 79,95%CI( -1. 47,-0. 11),P=0. 02〕. After the exclusion of low-quality literatures,the meta analysis showed that trial group was lower than control group in body mass,BMI,body fat rate and waistline〔MD= -0. 95,95%CI( -1. 64,-0. 26),P=0. 007;MD= -0. 36,95%CI( -0. 64,-0. 07),P=0. 01;MD= -0. 74,95%CI( -1. 27,-0. 21), P=0. 006;MD= -0. 81,95%CI( -1. 50,-0. 13),P =0. 02〕. The publication bias test showed that no significant publication bias occurred in body mass,BMI,body fat rate and waistline(Z=0. 49,P=0. 624;Z=1. 17,P=0. 243;Z=0. 79,P=0. 428;Z=0. 26,P=0. 792). Conclusion Tea catechins has no significantly influencing for body weight,BMI, body fat rate and waistline in adults,but catechin-caffeine mixture significantly reduce body weight,BMI,body fat rate and waistline. The effect is more obvious in Asian.%目的：定量评价儿茶素对超重/肥胖成年人群的影响。方法计算机检索Cochrane图书馆、PubMed、EMBase、中国知网（ CNKI）、中国生物医学文献数据库（ CBMdisc）、维普中文科技期刊、万方中文数据库，检索时限从建库至2013年。收集试验组服用含有高剂量儿茶素制成的饮料、片剂或胶囊，对照组为安慰剂对照、饮品对照或低剂量儿茶素对照的随机对照试验（ RCT）。对纳入文献进行质量评价和数据提取，采用统计学软件对体质量、体质指数（ BMI）、体脂率和腰围进行分析。结果共纳入25篇文献，提取29项RCT试验记录，包括2191例患者，其中试验组1187例，对照组1004例；29项试验中22项为高质量研究（≥4分），7项为低质量研究（＜4分）。Meta分析结果显示，试验组体质量、BMI、体脂率和腰围均较对照组（非亚洲人）降低〔MD ＝-0.89，95％CI（-1.46，-0.32），P＝0.002；MD ＝-0.32，95％ CI（-0.56，-0.09），P ＝0.007；MD ＝-0.75，95％ CI（-1.27，-0.24），P＝0.004；MD＝-0.66，95％CI（-1.24，-0.07），P＝0.03〕。亚组分析结果显示，试验组（儿茶素和咖啡因混合物）体质量、BMI、体脂率和腰围均较对照组（有咖啡因匹配）降低〔MD ＝-0.97，95％CI（-1.31，-0.64），P＜0.001；MD ＝-0.40，95％ CI（-0.54，-0.26），P ＜0.001；MD ＝-0.90，95％ CI（-1.39，-0.42），P＝0.0003；MD＝-1.16，95％CI（-1.99，-0.34），P＝0.006〕；试验组（亚洲人）体质量、BMI、体脂率和腰围均较对照组（非亚洲人）降低〔MD＝-1.01，95％CI（-1.63，-0.38），P＝0.002；MD＝-0.41，95％CI （-0.67，-0.16），P ＝0.002；MD ＝-1.21，95％ CI（-1.86，-0.57），P ＝0.0002；MD ＝-0.79，95％ CI （-1.47，-0.11），P＝0.02〕。排除低质量文献后进行Meta分析，结果显示，试验组体质量、BMI、体脂率和腰围均较对照组降低〔MD＝-0.95，95％CI（-1.64，-0.26），P＝0.007；MD＝-0.36，95％CI（-0.64，-0.07），P＝0.01；MD＝-0.74，95％CI（-1.27，-0.21），P＝0.006；MD＝-0.81，95％CI（-1.50，-0.13），P＝0.02〕。发表偏倚检测结果显示，体质量、BMI、体脂率和腰围均无显著的发表偏倚（ Z ＝0.49，P ＝0.624；Z ＝1.17，P ＝0.243；Z＝0.79，P＝0.428；Z＝0.26，P＝0.792）。结论单独儿茶素对超重/肥胖人群体质量、BMI、体脂率和腰围无降低作用，而儿茶素和咖啡因混合物可以降低超重/肥胖人群体质量、BMI、体脂率和腰围，在亚洲人中影响更显著。
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