Objective To explore the pathological features and prognostic factors for cervical cancer patients in Han and Uygur patients. Methods Data of 138 Chinese and Uygur cervical cancer patients admitted into Xinjiang Medical University from January 2005 to December 2009 were collected and reviewed. The patients were followed up for 5 years. Prognostic factors were analyzed retrospectively. Results The 5 - year survival rates were 78. 2％ , of which the 5 - year survival rates in Han and Uygur patients were 85％ and 73％ , respectively. The five - year survival rates of patients with the parity ＜ 3 or≥ 3 times were 8. 1％ and 59. 5％ . Uygur and Han patients with cervical cancer were significantly different in the parity ( x2 = 21. 953 , P =0. 000 ), pathologic type ( x2 = 5. 353 , P = 0. 021 ) and clinical stage ( U = 1512, P = 0. 000 ). Univariate analysis showed that parity, pathological type, clinical stage , lymph node metastasis , tumor size ( FIGO stage ) and the treatment impact on the 5 - year survival rates were important ( P ＜0. 05 ). Multivariate analysis showed that the tumor size, histology clinical stage and operation were independent prognostic factors for cervical cancer patients ( the values of P were 0. 004 , 0. 000 , 0. 000 and 0. 018 respectively ). Conclusion The incidence of cervical cancer is lower, and the stage is earlier in Uyger patients than in Han patients. Parity, pathological type, clinical stage, lymph node metastasis, tumor size and treatment approach are prognostic factors for cervical cancer patients, of which parity , pathological type, clinical stage and treatment approach are important prognostic factors. Uyger and Han cervical cancer patients who has a parity of more than three times , and who is in late clinical stage and who has radiotherapy , all have low survival rate and bad prognosis.%目的 探讨维吾尔族(维族)和汉族早期宫颈癌患者的临床病理特点、预后及其影响因素.方法 纳入在新疆医科大学第一附属医院2005年1月-2009年12月收治的138例早期宫颈癌患者,并随访5年后以死亡为结局,回顾性分析影响预后的因素.结果 138例宫颈癌患者的5年生存率为78.2%,其中汉族和维族患者5年生存率分别为85%和73%,产次＜3次与产次≥3次患者5年生存率分别为 8.1%和59.5%.维族和汉族宫颈癌患者在产次(x2=21.953,P=0.000)、病理类型(x2=5.353,P=0.021)、临床分期(u=1512,P=0.000)间差异有统计学意义.单因素分析显示不同的产次、病理类型、临床分期、淋巴结转移、肿瘤大小(国际妇产科联盟分期)和治疗方式对5年生存率的影响均有统计学意义(P＜0.05).多因素分析显示产次、病理类型、临床分期、治疗方式对5年生存率的影响有统计学意义(P值分别为0.004、0.000、0.000和0.018).结论 维族腺癌发病率低于汉族,且肿瘤分期相对较早.产次、病理类型、临床分期、淋巴结转移、肿瘤大小和治疗方式是维汉早期宫颈癌预后的影响因素,其中产次、病理类型、临床分期、治疗方式为重要的预后影响因素.维汉早期宫颈癌患者产次≥3次、临床分期越晚以及术后单纯放疗生存率低、预后差.
展开▼
