Objective To analyze the gap hetween grassroots hospitals and upper first - class hospitals in the diagnosis and treatment of peptic ulcer bleeding. Methods Sixty - one patients hospitalized at Puren Hospital from January 2000 to June 2010 due to peptic ulcer bleeding were enrolled as the case group, while 122 matched patients at the Third Hospital of Peking U-niversity were enrolled as controls. Retrospective analysis were carried out concerning endoscopic features , Helicobacter pylori infection, tumor marker evaluation, treatment and prognosis of the two groups. Results Detection rate of endoscopy, Helicobacter pylori, and tumor marker evaluation together with proton pump inhibitor usage between the two groups showed significant differences ( P＜0.01 ) . Rebleeding rate during hospital stay between the two groups showed no significant difference ( P ＞ 0.05 ).Timespan distribution for the negative conversion of occult hlood was significantly different between the two groups ( P ＜ 0.05 ).Conclusion Gaps exist between upper first - class hospitals and grassroots hospitals in several aspects including emergency endoscopy rate, medication, Helicobacter pylori testing and eradication treatment. Timespan for the negative conversion of occult blood in occult blood negative conversion during hospitalization in upper first - class hospitals is relatively shorter.%目的 分析基层医院与三级甲等医院在消化性溃疡合并出血诊治方面的差距.方法 选择2000年1月-2010年6月因消化性溃疡合并出血入住北京市普仁医院(普仁医院)治疗的61例患者为病例组,按成组匹配原则选取北京大学第三医院(北医三院)住院的122例患者为对照组,回顾性分析两组胃镜检查,幽门螺杆菌、肿瘤标记物检测,治疗及预后情况.结果 两组胃镜检出率、幽门螺杆菌检出率、肿瘤标记物检查率、质子泵抑制剂使用率比较,差异均有统计学意义(P＜0.01).两组住院期间再出血率比较,差异无统计学意义(P＞0.05);而便隐血阴转时间分布比较,差异有统计学意义(P＜0.05).结论 基层医院在急诊胃镜检查率、药物治疗以及幽门螺杆菌的检测及根除幽门螺杆菌治疗方面与三级甲等医院相比均有差距,三级甲等医院患者住院期间便隐血转阴时间较短.
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