目的：探寻早期诊断前列腺癌的方法。方法应用超声弹性成像（UE）技术，对56例前列腺增生伴PSA增高或正常患者，同时行经直肠前列腺二维超声及UE检查，比较普通经直肠超声检查联合PSA与UE联合PSA对前列腺癌诊断的敏感性和特异性。结果以穿刺活检为判断前列腺癌的标准，UE联合PSA无论是敏感性（75.0%）、特异性（85.0%）和符合率（82.1%）均高于普通经直肠超声检查联合PSA敏感性（62.5%）、特异性（15.0%）和符合率（28.6%），差异具统计学意义（P＜0.05）。结论 UE无痛无创，简便易行，其与PSA相结合对前列腺癌的诊断，比经直肠超声检查联合PSA更具有临床价值，值得推广。%Objective To improve the early diagnostic rate of prostate cancer using simple and noninvasive elasticity imaging techniques.Methods Total of 56 cases with hyperplasia of prostate whose had high level of serum PSA or normal level of serum level were examined by rectum prostate two-dimensional ultrasound, ultrasonic elastography imaging and biopsy technology, respectively. The diagnostic sensitivity and specificity of common transrectal ultrasound joint PSA and elastography joint PSA for prostate cancer were comparatively analyzed.Results Taking biopsy results as a diagnostic standard of prostate cancer, sensitivity of the elasticity imaging joint PSA (75%, 85%, 82.1%) were significantly higher than that of common transrectal ultrasonography joint PSA(62.5%, 15%, 28.6%) (P<0.05).Conclusion Ultrasonic elastography is a painless and simple diagnostic method for prostate cancer, it combining with PSA detection is superior to common transrectal ultrasonography joint PSA detection in the diagnosis of prostate cancer, which deserved to be applied in clinic.
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