This study was conducted to investigate the effects of composite plant extracts(CPE)(from grana-tum, argy wormwood leaf, Kadsura japonica L. and Fructus evodiae rutaecarpae)replacing feed antibiotics on growth performance and serum indexes of weaned piglets. In experiment 1, a total of 160 weaned piglets weighted about 8 kg at about 30 days of age were selected and randomly allocated into 4 groups with 4 repli-cates per group and 4 piglets per replicate. Piglets in different groups were fed a basal diet supplemented with aureomycin 107 mg/kg+flavomycin 40 mg/kg(control)and CPE at 0.05%,0.10% and 0.20% for 28 d,re-spectively. In experiment 2, a total of 120 weaned piglets weighted about 11 kg at about 40 days of age were selected and randomly allocated into 3 groups. Piglets in antibiotic-free group were fed the basal diet,and those in the other two groups were fed the basal diet supplemented with aureomycin 67 mg/kg+flavomycin 20 mg/kg (antibiotics group)and CPE at 0.10% for 35 d, respectively. The results of experiment 1 showed as follows:compared with control group, average daily gain(ADG), average daily feed intake(ADFI)and feed/gain (F/G)of CPE groups were not significantly changed(P>0.05), and 0.10% CPE group had better ADG, which was 2.44% higher than control group(P>0.05). The results of experiment 2 showed as follows: com-pared with antibiotic-free group, in 0.10% CPE group, ADG was significantly increased by 21.39%(P<0.05), the contents of serum albumin(ALB), cholesterol(CHOL), low density lipoprotein-cholesterol (LDL-C)and nitric oxide(NO)were significantly decreased(P<0.05), serum glutathione peroxidase (GSH-Px)activity was significantly increased(P<0.05), and serum ceruloplasmin(CER)activity was sig-nificantly decreased(P<0.05);compared with antibiotic group,in 0.10% CPE group,ADG was significantly increased by 15.07%(P<0.05),the contents of serum urea nitrogen(UN),LDL-C and NO were significant-ly decreased(P < 0. 05). Collectively, CPE supplementation at 0. 10% can replace feed antibiotics (aureomycin+flavomycin), improve growth performance, and has anti-stress and anti-oxidation functions in weaned piglets.%本试验旨在研究饲粮中添加复合植物(含石榴皮、艾叶、南五味子和吴茱萸)提取物替代饲用抗生素对断奶仔猪生长性能和血清指标的影响.试验1:选取8 kg、30日龄左右的断奶仔猪160头,随机分为4组,各组分别在基础饲粮中添加金霉素107 mg/kg+黄霉素40 mg/kg (对照)及0.05%、0.10%和0.20%的复合植物提取物,每组4个重复,每个重复10头仔猪,试验期28 d.试验2:选取11 kg、40日龄左右的断奶仔猪120头,随机分为3组,无抗组采用基础饲粮,另外2组分别在基础饲粮中添加金霉素67 mg/kg+黄霉素20 mg/kg(抗生素组)和0.10%的复合植物提取物组,试验期35 d.试验1结果显示:与对照组相比,各复合植物提取物组仔猪平均日增重(ADG)、平均日采食量(ADFI)和料重比(F/G)均无显著变化(P>0.05),且0.10%的添加量具有较好的ADG,比对照组提高2.44%.试验2结果显示:与无抗组相比,0.10%的复合植物提取物可使仔猪 ADG 显著提高21.39%(P<0.05),使血清中白蛋白(ALB)、胆固醇(CHOL)、低密度脂蛋白胆固醇(LDL-C)和一氧化氮(NO)含量均显著降低(P<0.05),谷胱甘肽过氧化物酶(GSH-Px)活力显著升高(P<0.05),铜蓝蛋白(CER)活力显著降低(P<0.05);与抗生素组相比,0.10%的复合植物提取物可使仔猪ADG显著提高15.07%(P<0.05),使血清中尿素氮(UN)、LDL-C和NO含量均显著降低(P<0.05).综上所述,0.10%的复合植物提取物可替代饲用抗生素(金霉素+黄霉素),提高仔猪的生长性能,具有抗应激和抗氧化功能.
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