To study the Effection on Tong Mai Ning for preventing and treating diabetic complications of blood vessel,we perfuse stomach of DM rats induced by STZ with Tang Mai Ning (2kg/kg*d) in 8 weeks. Results show that Tang Mai Ning can decrease the levels of blood sugar,blood lipid,blood viscosity and blood endothelin,increase the activity of the SOD and decease the levels of the LPO in tissues of heart and kidney, and can prevent kidney frome pathologic change. Conclusion:Tang Mai Ning may effectively prohibit diabetic complication of blood vessels.%用复方中药制剂糖脉宁2g/kg*d灌胃连续8周，观察其对STZ所致糖尿病大鼠的影响。结果：糖脉宁除具有一定降血糖作用外，还具有降血脂，降低血黏度及血浆ET水平，提高心、肾组织SOD活性，降低LPO水平的作用，并可防止肾组织病理改变发生。结论：糖脉宁对防治糖尿病血管并发症是十分有益的。
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