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Comparison of Heart Rate Variability between Normoxia and Hypobaric Hypoxia Exposure

         

摘要

This study aimed to use the sample entropy(Samp En)method to compare the difference between normoxia and hypobaric hypoxia exposure in heart rate variability.Eight healthy male volunteers were included in this research.For each subject,electrocardiography and finger pulse signal were recorded to obtain the heart rate time series.The Sp O2 signal was collected at the same time.In normoxia or hypobaric hypoxia 4300 m section,the segment of RR time series from the second5 min episode(from the 6 th to the 10 th min)was chosen for the Samp En calculation.The differences between normoxia and hypobaric hypoxia states were analyzed.Results showed that a significant difference exists in Samp En between two states(normoxia 0.54±0.05 vs hypobaric hypoxia 4300 m exposure 0.46±0.05),indicating the regulatory mechanisms of autonomic nervous system from a nonlinear perspective.

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    Institute of Biomedical Engineering School of Control Science and Engineering Shandong University Jinan Shandong 250061 China;

    Air Force Medical Center PLA Beijing 100142 China;

    Air Force Medical Center PLA Beijing 100142 China;

    Air Force Medical Center PLA Beijing 100142 China;

    Medical Big Data Research Center Chinese PLA General Hospital Beijing 100853 China;

    Department of Medical Engineering Management Shandong Provincial Hospital Affiliated to Shandong First Medical University Jinan Shandong 250021 China;

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