Inflammaging is a new branch in aging-related research field.It describes the pro-inflammatory state associated with aging,with the characteristics including low grade,controlled,asymptomatic,chronic,and systemic.The major task of studying inflammaging is that it provides prediction in aging-related diseases in order to offer prompt meas-ures to intervene and better reaching the goal of healthy aging.This article will systematically reviewe the close relation-ship between inflammatory cytokines including interleukin-6,C reactive protein and tumor necrosis factor-αand multiple chronic conditions including caridovascular and cerebrovascular events,type 2 diabetes and frailty,etc.%炎性衰老是衰老研究领域的一个新概念,是指衰老过程中促炎反应的慢性、进行性升高的现象;主要特点是低滴度、系统性、无症状的、可控的慢性炎性反应.研究炎性衰老能够为老年病提供更为准确的预测,尽早给予适当干预,达到健康老龄化的目的.此综述系统性回顾了近年来炎性衰老标志物白介素6、C反应蛋白及肿瘤坏死因子α等血清炎性因子与常见老年病,包括心脑血管事件、2型糖尿病及衰弱等之间的关系,有助于指导老年病的防治.
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