Objective Idiopathic ventricular arrhythmias tends to occur in patients without structural heart disease.The aim of the study was to investigate the heart rate variability in patients with idiopathic ventricular arrhyth -mias ( IVA) .Methods Patients with idiopathic ventricular arrhythmias who underwent catheter mapping and radio -frequency catheter ablation were admitted to the hospital during March 1998 and December 2012 .The heart rate varia-bility in patients with different origins of IVA were retrospectively analyzed and compared .Results A total of 116 pa-tients with idiopathic ventricular arrhythmias were selected .originated from the RVOT was 80 cases,LVOT 12 cases, left ventricular septal 9 cases,right ventricular inflow tract 7 cases,the other left ventricular 8 cases.Of all patients, there were no significant differences in the PVC frequency ,SDNN,SDANN,RMMSD,PNN50,LF,HF between the dif-ferent groups .Also,no significant difference was found for gender .There were significant differences in the proportion of patients between patients with LF/HF>1 and patients with LF/HF<1(47/116 vs 69/116,P<0.05).Conclusion The differences of heart rate variability in patients with different origins of IVA were found ,which suggests that the ANS may play a different role in development of IVA .%目的分析特发性室性心律失常(IVA)患者导管射频消融(RFCA)术前动态心电图的检测结果,探讨自主神经系统(ANS)在IVA形成机制中的作用。方法纳入116例解放军总医院住院行RFCA的患者。分析术前24h动态心电监护等资料,比较不同起源IVA的患者间心率变异性(HRV)指标的差异。结果116例患者中男性59例,女性57例,年龄10~82(43.3±15.7)岁。起源于右室流出道(RVOT)80例、左室流出道(LVOT)12例、左室间隔9例、右室流入道7例、左室其他部位8例。在5组患者间的24h室性早搏总数、正常窦性心律R-R间期标准差(SDNN)、正常窦性心律R-R间期平均值的标准差(SDANN)、全程相邻正常窦性心律R-R间期之差的均方根值(RMSSD)、在一定时间内相邻两正常心动周期差值>50ms的个数所占的百分比(PNN50)、低频功率(LF)、高频功率(HF)的差异无统计学意义;男性患者和女性患者组间的差异无统计学意义。LF/HF>1与LF/HF<1的患者组间相比构成比差异有统计学意义(P<0.05)。夜间23:00~7:00室早的次数占24小时总室性早搏的次数<30%组和>30%组,两组相比构成比差异有统计学意义(P<0.05)。结论不同起源部位的IVA患者的HRV存在差异,提示自主神经在不同起源部位的IVA发生过程中发挥不同的作用。
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