To invesligale the incidence oi non-alcoholic fatty liver disease ( NAFLD) in older palienls with essenlial hypertension and the relationship belween NAFLD and risk faclors. Methods 621 older pa-lienls wilh essenlial hypertension were enrolled into this study. All palienls had ultrasound screening for fatty liver. Results Among 621 recruiled palienls, 39. 1% ( 243/621) had fally liver by ullrasonography. In essenlial hypertension ( EH) logelher wilh NAFLD group, the prevalences of diabeles mellilus, coronary artery disease, melabolic syndrome, overweight, and the level of TG or ALT were significantly higher than those in the EH alone ( P <0. 05) . HDL-C was significantly lower lhan that in the EH alone ( P<0. 05) . By mullivariable logistic regression analysis, diabeles mellilus, coronary artery disease, overweight and TG were risk faclors of NAFLD in older patients with essenlial hypertension. Conclusion Non-alcoholic fatty liver disease is more prevalent in older patients with essenlial hypertension complicated with multiple metabolic disorders.%目的 探讨老年高血压患者非乙醇性脂肪性肝病的患病率和危险因素.方法 621例老年高血压患者住院期间经腹部超声检查和采集病史筛查非乙醇性脂肪性肝病(NAFLD),观察其患病率、肝功酶学异常的比例及其危险因素.结果 NAFLD患者发病率为39.1%(243/621).NAFLD组糖尿病,冠心病,代谢综合征发生率、超重率、三酰甘油、ALT水平高于非NAFLD组,HDL-C低于非NAFLD组,差异有统计学意义(P<0.05).糖尿病、冠心病、超重和三酰甘油水平是老年高血压患者NAFLD的独立危险因素.结论 老年高血压伴NAFLD患者与代谢综合征等多代谢异常密切相关.
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