目的 探讨脑卒中后抑郁症(PSD)的危险因素.方法 对196例脑卒中患者行头颅MRI或头颅CT检查以明确诊断,发病后6周内多次对患者进行汉密尔顿抑郁量表(HAMD)评分,共有65人确诊为PSD,分析PSD的发生与性别、年龄、文化程度、卒中性质、日常生活能力、独立行走和发病部位的关系.结果 日常生活能力明显障碍或不能独立行走的脑卒中患者PSD的发病率明显高于日常生活能力无明显障碍或能独立行走的患者(P＜0.05).左侧额叶卒中患者PSD的发病率高于其他部位脑卒中患者(P＜0.05).性别、年龄、文化程度、卒中性质不同的脑卒中患者PSD发生率差异无统计学意义.结论 急性期脑卒中患者PSD的发生与日常生活能力明显障碍、不能独立行走、左侧额叶卒中有关.%Objective To explore risk factors of post-stroke depression (PSD). Methods 196 stroke patients were diagnosed by MRI or CT. All patients were tested many times by the Hamilton Depression Scale ( HAMD) in six week after stroke and 65 patients with post-stroke depression were diagnosed. To analyze the relationship between PSD and the stroke patients with gender, age, culture level, stroke type, activity of dailing living, independent ambulation and lesion location. Results Patients with dependent ambulation or obviously disorder in activity of dailing living had higher incidence of PSD than that with independent ambulation or without obviously disorder in activity of dailing living (P < 0.05 ). Left frontal lobe lesion has higher incidence of PSD than the other location lesion in the brain (P<0.05). There was no difference in the incidence of PSD in stroke patients with different gender,age,culture level or stroke type (P≥0.05). Conclusion PSD is related to dependent ambulation,obviously disorder in activity and left frontal lobe lesion.
展开▼
